Research Associate position to study the bacterial type VI secretion system
We wish to recruit a Research Associate to work with Paul. Our research group comprises research fellows, research associates and PhD students from a diverse range of backgrounds including molecular biology, biochemistry, X-ray crystallography, electron microscopy, physics and engineering. We employ a multi-disciplinary approach to study the structures and mechanisms of large macromolecular complexes.
The post is funded for up to five years by a MRC programme grant to Paul in collaboration with Prof. Alain Filloux. The successful candidate will join a multi-disciplinary group to investigate the structure and function of the Type VI secretion system in Pseudomonas aeruginosa. You will be responsible for carrying out structural studies of these key complexes.
You must hold a PhD in a structural biology or biochemistry discipline. You must have advanced knowledge of protein biochemistry and structural biology and be able to demonstrate the capacity for innovative, high quality structural biological research. Research experience in a structural biological laboratory environment covering X-ray crystallography or electron microscopy single particle analysis is essential. Experience of reconstituting and characterising large multi-protein complexes is also desirable.
You must be able to work effectively within a team, have the ability to develop and apply new concepts, and have a creative approach to problem-solving. You must have excellent verbal and written communication skills, and be able to write clearly and succinctly for publication. Experience in the supervision and training of junior research staff and students, and in writing scientific research papers would be an advantage.
Salary will be in the range of £32,100 - £40,720 per annum.
Closing date for applications is 24 May 2013 (Midnight BST)
Please apply online and quote reference NS 2013 084 IL
Two PhD projects funded through the BBSRC Doctoral Training Partnership (DTP) based at Imperial College are availabe in Xiaodong's lab. Both studentships will be offered on a 1+3 basis (1 Year of Masters study followed by 3 years of PhD Research). In either case, the Masters Course will commence in October 2013 followed by the commencement of the PhD in October 2014. Very exceptionally, applicants with an appropriate Masters Degree can be considered for direct entry into a 3 year PhD programme.
The aim of the first project is to study the structure and function of the translocon of the bacterial type III secretion system. The second project concerns the molecular mechanism of transcriptional regulation via AAA ATPases. If you're interested in either project, please contact .
In addition, applications are invited for the 1-year MRes and 3 to 4-year PhD programmes in Structural Molecular Biology.
MRes in Structural Biology
As part of the Centre for Structural Biology, we organise a one-year MRes course, giving in-depth practical experience of techniques relevant to structural biology.