Macromolecular Structure and Function

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Welcome to the Zhang/Freemont Labs

We are a multidisciplinary laboratory interested in understanding how the three-dimensional structure of proteins relates to their function.  Using a variety of techniques, we work on determining the structures of proteins and multi-protein complexes to near-atomic detail.  We also employ a wide variety of biochemical techniques to enable collection and analysis of functional data.  The use of complementary techniques enables us to build detailed models that explain the structure/function relationships that exist in our target proteins.

The laboratory unites the groups of Prof. Xiaodong Zhang and Prof. Paul S Freemont.  We are part of the Centre for Structural Biology in the Division of Molecular Biosciences at Imperial College.